Home Stocks Super Investors
Investor

BAKER BROS. ADVISORS LP

Portfolio Total Value

$9,130,597,000.00

Number of Stocks

79

Period of Reporting

2024-12-31

Stocks

Stock Value % Recent Activity Share Reported Price Current Price +/- Reported Price 52 Week Low 52 Week High
INCY $2,123,174,000.0 23.3%
Added 0.0%
30,739,466 $69.07 $100.04
Added 44.84%
$50.35 $83.95
BGNE $1,760,633,000.0 19.32%
Reduced 9.81%
9,531,880 $184.71 $0.0
Reduced 100.0%
$0.0 $0.0
ACAD $786,809,000.0 8.63%
No Change
42,877,916 $18.35 $22.81
Added 24.31%
$14.15 $29.29
MDGL $609,299,000.0 6.69%
No Change
1,974,590 $308.57 $435.62
Added 41.17%
$168.25 $368.29
SMMT $435,861,000.0 4.78%
No Change
24,424,865 $17.85 $16.19
Reduced 9.3%
$2.1 $33.89
RVMD $347,163,000.0 3.81%
Added 4.86%
7,936,972 $43.74 $101.62
Added 132.33%
$26.95 $62.4
INSM $345,673,000.0 3.79%
Added 13.38%
5,006,863 $69.04 $146.32
Added 111.94%
$21.92 $80.53
RYTM $340,596,000.0 3.74%
Reduced 4.91%
6,084,249 $55.98 $94.94
Added 69.6%
$35.17 $68.58
KYMR $241,216,000.0 2.65%
No Change
5,995,929 $40.23 $90.1
Added 123.96%
$29.24 $53.27
KOD $172,239,000.0 1.89%
No Change
17,310,490 $9.95 $27.36
Added 174.97%
$2.19 $11.6
EWTX $164,363,000.0 1.8%
Added 5.41%
6,155,940 $26.7 $29.7
Added 11.24%
$14.9 $38.12
BCYC $152,394,000.0 1.67%
Added 15.8%
10,885,357 $14.0 $5.73
Reduced 59.07%
$12.17 $28.67
REPL $133,759,000.0 1.47%
No Change
11,045,336 $12.11 $7.16
Reduced 40.88%
$4.92 $17.0
ALKS $120,267,000.0 1.32%
No Change
4,181,751 $28.76 $30.25
Added 5.18%
$22.9 $32.88
$92,928,000.0 1.02%
No Change
42,850,000 $2.17 $nan
Reduced nan%
$nan $nan
TRDA $84,130,000.0 0.92%
No Change
4,865,819 $17.29 $11.68
Reduced 32.45%
$11.35 $21.79
ABCL $80,650,000.0 0.89%
No Change
27,525,640 $2.93 $3.82
Added 30.38%
$2.34 $5.62
DNLI $76,051,000.0 0.83%
No Change
3,731,695 $20.38 $21.0
Added 3.04%
$14.56 $33.33
NRIX $73,139,000.0 0.8%
No Change
3,882,125 $18.84 $15.81
Reduced 16.08%
$7.65 $29.56
ARGX $68,820,000.0 0.76%
No Change
111,904 $615.0 $756.76
Added 23.05%
$349.86 $678.21
RARE $66,307,000.0 0.73%
No Change
1,576,114 $42.07 $23.02
Reduced 45.28%
$37.02 $60.37
IMTX $51,731,000.0 0.57%
Added 12.92%
7,275,830 $7.11 $9.99
Added 40.51%
$5.28 $13.77
CRSP $51,483,000.0 0.56%
Added 55.15%
1,308,011 $39.36 $60.77
Added 54.4%
$36.52 $91.1
STOK $51,111,000.0 0.56%
Added 6.08%
4,633,838 $11.03 $36.69
Added 232.64%
$4.09 $17.58
IMCR $44,701,000.0 0.49%
No Change
1,515,318 $29.5 $32.67
Added 10.75%
$27.69 $76.98
ROIV $44,572,000.0 0.49%
Added 34.63%
3,767,773 $11.83 $28.1
Added 137.53%
$9.69 $13.06
SERA $44,236,000.0 0.49%
No Change
5,434,399 $8.14 $2.23
Reduced 72.6%
$4.98 $12.36
IMVT $42,304,000.0 0.46%
Added 39.37%
1,707,881 $24.77 $27.75
Added 12.03%
$22.41 $40.12
XENE $38,952,000.0 0.43%
No Change
993,679 $39.2 $42.55
Added 8.55%
$35.53 $50.99
CELC $35,062,000.0 0.38%
Added 42.86%
2,678,553 $13.09 $108.3
Added 727.35%
$10.35 $22.19
GLUE $34,117,000.0 0.37%
No Change
4,916,095 $6.94 $18.5
Added 166.57%
$3.21 $12.4
CERS $29,995,000.0 0.33%
No Change
19,477,339 $1.54 $2.53
Added 64.29%
$1.38 $2.59
AKRO $30,520,000.0 0.33%
No Change
1,097,082 $27.82 $0.0
Reduced 100.0%
$0.0 $0.0
IDYA $27,296,000.0 0.3%
No Change
1,062,123 $25.7 $33.04
Added 28.56%
$22.1 $47.74
KRYS $26,621,000.0 0.29%
No Change
169,934 $156.66 $258.81
Added 65.2%
$107.5 $219.34
CADL $25,883,000.0 0.28%
No Change
2,981,983 $8.68 $5.11
Reduced 41.13%
$1.16 $14.6
IGMS $25,016,000.0 0.27%
Added 0.05%
4,094,304 $6.11 $0.0
Reduced 100.0%
$0.0 $0.0
CNTA $20,555,000.0 0.23%
No Change
1,227,178 $16.75 $26.51
Added 58.27%
$7.38 $18.97
MRUS $18,922,000.0 0.21%
Added 50.0%
450,000 $42.05 $90.0
Added 114.03%
$33.6 $61.61
XNCR $15,406,000.0 0.17%
No Change
670,431 $22.98 $12.3
Reduced 46.48%
$15.31 $27.24
DYN $15,834,000.0 0.17%
No Change
672,096 $23.56 $16.15
Reduced 31.45%
$13.99 $47.45
IONS $12,512,000.0 0.14%
Added 60.16%
357,915 $34.96 $81.96
Added 134.44%
$31.4 $52.49
PRLD $12,907,000.0 0.14%
No Change
10,123,824 $1.28 $2.71
Added 111.72%
$0.8 $6.8
DSGN $10,758,000.0 0.12%
No Change
1,743,725 $6.17 $10.23
Added 65.8%
$2.25 $7.77
VERV $9,540,000.0 0.1%
No Change
1,691,530 $5.64 $0.0
Reduced 100.0%
$0.0 $0.0
ARVN $7,774,000.0 0.09%
No Change
405,576 $19.17 $13.39
Reduced 30.15%
$17.08 $53.08
VIR $7,960,000.0 0.09%
No Change
1,084,539 $7.34 $9.34
Added 27.25%
$6.56 $14.45
MIRM $7,876,000.0 0.09%
No Change
190,476 $41.35 $90.09
Added 117.87%
$23.14 $48.89
OPT $8,536,000.0 0.09%
No Change
2,173,622 $3.93 $0.0
Reduced 100.0%
$0.0 $0.0
TCRX $8,465,000.0 0.09%
No Change
2,784,792 $3.04 $1.05
Reduced 65.46%
$2.31 $9.69
TSHA $6,928,000.0 0.08%
No Change
4,004,756 $1.73 $4.53
Added 161.85%
$1.19 $4.32
TSVT $7,342,000.0 0.08%
No Change
2,497,526 $2.94 $0.0
Reduced 100.0%
$0.0 $0.0
NTLA $7,510,000.0 0.08%
No Change
644,116 $11.66 $15.44
Added 32.42%
$9.25 $34.87
CLDX $6,257,000.0 0.07%
No Change
247,644 $25.27 $30.0
Added 18.72%
$22.17 $53.18
BMEA $5,633,000.0 0.06%
Reduced 31.15%
1,451,990 $3.88 $1.37
Reduced 64.69%
$3.61 $20.21
BNTX $5,131,000.0 0.06%
No Change
45,031 $113.95 $107.48
Reduced 5.68%
$76.53 $131.49
TNGX $5,775,000.0 0.06%
No Change
750,000 $7.7 $11.53
Added 49.74%
$2.59 $13.01
CRNX $5,310,000.0 0.06%
No Change
103,927 $51.1 $40.68
Reduced 20.39%
$35.51 $62.53
FATE $5,376,000.0 0.06%
Added 8.69%
3,258,402 $1.65 $1.5
Reduced 9.09%
$1.04 $8.83
RLAY $4,779,000.0 0.05%
No Change
1,160,117 $4.12 $9.79
Added 137.62%
$3.5 $11.16
WVE $4,256,000.0 0.05%
No Change
344,063 $12.37 $13.85
Added 11.96%
$3.5 $16.74
ALEC $4,321,000.0 0.05%
No Change
927,264 $4.66 $2.21
Reduced 52.58%
$1.6 $7.58
PCVX $4,001,000.0 0.04%
No Change
48,885 $81.86 $61.98
Reduced 24.29%
$58.1 $121.06
SANA $3,880,000.0 0.04%
No Change
2,380,949 $1.63 $4.15
Added 154.6%
$1.52 $12.0
TARA $2,834,000.0 0.03%
No Change
536,832 $5.28 $5.97
Added 13.07%
$1.6 $10.48
ARCT $2,568,000.0 0.03%
No Change
151,329 $16.97 $8.35
Reduced 50.8%
$14.3 $45.0
CMPX $2,258,000.0 0.02%
No Change
1,557,630 $1.45 $5.68
Added 291.72%
$0.77 $2.73
GBIO $2,061,000.0 0.02%
No Change
1,944,945 $1.06 $5.34
Added 403.77%
$0.75 $4.65
MRSN $1,553,000.0 0.02%
No Change
1,086,115 $1.43 $29.08
Added 1933.57%
$0.53 $6.28
AVTE $1,314,000.0 0.01%
No Change
628,939 $2.09 $0.0
Reduced 100.0%
$0.0 $0.0
BCRX $575,000.0 0.01%
No Change
75,778 $7.6 $8.63
Added 13.55%
$4.03 $8.88
RCKT $1,220,000.0 0.01%
No Change
97,079 $12.57 $4.97
Reduced 60.46%
$10.1 $31.47
IPSC $805,000.0 0.01%
No Change
797,460 $1.01 $2.26
Added 123.76%
$0.87 $5.51
PMVP $486,000.0 0.01%
No Change
322,024 $1.51 $1.8
Added 19.21%
$1.32 $2.26
PTCT $920,000.0 0.01%
No Change
20,400 $45.14 $66.37
Added 47.03%
$23.58 $54.16
PFE $1,012,000.0 0.01%
No Change
35,000 $28.94 $27.26
Reduced 5.81%
$24.48 $31.54
FHTX $212,000.0 0.0%
No Change
45,027 $4.72 $5.76
Added 22.03%
$2.7 $10.25
SRZNW $17,000.0 0.0%
No Change
833,333 $0.02 $0.02
No Change
$0.05 $0.05
TYRA $147,000.0 0.0%
No Change
10,607 $13.9 $32.52
Added 133.96%
$12.34 $29.6